Several populace-oriented studies and observational studies have shown you to oophorectomy is related that have a greater chance of colorectal cancers (CRC), and hormones replacement medication could have been on the a decrease in the risk of colorectal cancers. This study is achieved to analyze whether or not hysterectomy, which may affect the amounts of women hormone, are of this a risk of cancer tumors of one’s specific intestinal tract.

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That it populace-based retrospective cohort analysis are used using insurance policies data provided by the medical Insurance coverage Opinion and you may Analysis Service (HIRA) off . The brand new hysterectomy category provided forty- so you can 59-year-old ladies who undergone hysterectomy having uterine leiomyoma otherwise uterine endometriosis out-of . The control classification integrated feminine aged 40 so you’re able to 59 many years which went to scientific establishments getting scientific examination regarding .

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The brand new hysterectomy and you may low-hysterectomhy teams made-up 66,204 and 89,768 sufferers, correspondingly. The median ages regarding the low-hysterectomy classification and you will hysterectomy group was indeed forty-eight (range: 43–53) and you can 46 (range: 44–49) years, correspondingly. From the unadjusted results of the study, every colorectal cancer tumors (CRC) improved regarding hysterectomy alone classification (Hour step 1.222, 95% depend on period (CI) 1.0step one6–step 1.47, p = 0.033), sigmoid colon cancer enhanced regarding hysterectomy alone category (Hr step 1.71, 95% CI step 1.073–2.724, p = 0.024), and rectal malignant tumors improved regarding hysterectomy that have adnexal procedures classification (Hours step 1.924, 95% CI 1.073–2.724, p = 0.002). (mer …)